►The Imaging Core of the UC Irvine Core Center for Hearing and Communication Research was established in 2007 to provide state-of-the-art technology and expertise for imaging neurons in fixed or live tissue. 

    The Core features a 2-photon imaging system that was “home-made” for greater flexibility and performance, and for significant cost savings, over commercial models. 

    The system is capable of real-time imaging with high spatial resolution.

► Center for Hearing Research Multi-Photon Imaging Facility

► After ~1.5 years of development and operation, the facility is functional and serving multiple users.  The microscope is being used to image neurons in a variety of fixed- and live-tissue preparations, e.g., after transport of fluorescent markers or after immunofluorescent labeling.

► Calyces of Held in fixed tissue (left) and nucleus laminaris neurons in live slice culture (right).

► Contact

Karina Cramer, Ph.D. , CHR Imaging Core

                  Associate Professor and Director, cramerk@uci.edu

Candace Y. Hsieh, Ph.D. , CHR Imaging Core

                 Specialist, candace@uci.edu

Address: 2113A McGaugh Hall

                University of California, Irvine, Irvine, CA 92697

Telephone: (949) 824 7515